POSSIBLE SYNTHETIC APPROACHES FOR HETEROBIMETALLIC COMPLEXES BY USING NNHC/TZNHC HETERODITOPIC CARBENE LIGANDS

Possible Synthetic Approaches for Heterobimetallic Complexes by Using nNHC/tzNHC Heteroditopic Carbene Ligands

The synthesis of heterobimetallic complexes remains a synthetic challenge in the field of organometallic chemistry.A possible approach in this regard might be the use of a bidentate heteroditopic bis(carbene) ligand that combines an imidazol-2-ylidene (nNHC) with a 1,2,3-triazol-5-ylidene (tzNHC) connected by an organic spacer.The optimized strateg

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Lessons learned implementing and managing the DIVERT-CARE trial: practice recommendations for a community-based chronic disease self-management model

Abstract Background Chronic disease management models of care provide an opportunity to assist home care clients to manage their disease burden.However, pragmatic trial management practices and lessons learned from such models are poorly illustrated in the literature.Methods We describe the processes of implementing a community-based cardiorespirat

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Geographical distribution and genetic characterization of pfhrp2 negative Plasmodium falciparum parasites in the Peruvian Amazon

Malaria rapid diagnostic tests (RDTs) have been evaluated in the Peruvian Amazon region and their performance has been variable.This region is known for being the first with documented evidence of wild Plasmodium falciparum parasites lacking pfhrp2 and pfhrp3 genes, leading to false-positive results with HRP2-based RDTs.In our attempt to Brandy Gla

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